Europe – Amino Acid Mixtures / Medical Nutrition

Manufacturers and Product Lines

  • Vitaflo (Nestlé Health Science)
    • PKU start™ – phenylalaninfreie Aminosäurenbasis für Säuglinge/Kindergartenalter. (nestlehealthscience.de)
    • PKU explore™
    • PKU sphere™
    • PKU squeezie®
    • PKU express®
    • PKU cooler®
    • PKU air®
    • PKU sphere® liquid — various dosage forms for different age groups and preferences.(nestlehealthscience.de)
  • Nutricia Metabolics / SHS International (Danone)
    • Nutricia PKU GMPro LQ (neutral)
    • Nutricia PKU GMPro Delight 15 & 20 (verschiedene Geschmacksrichtungen)
    • Nutricia PKU 1-infant – für Säuglinge
    • Milupa PKU 2-prima / PKU 2-mix / PKU 2-shake / PKU 3-advanta –
      • age-specific formulations for toddlers through adolescents
    • (nutricia-metabolics.de)
    • PKU Anamix (various flavors) – protein-free amino acid mixtures with micronutrients. (nutricia-metabolics.de)
  • XPhe-Produkte
    • XPhe Infant Mix LCP –
      • for newborns and infants
    • XPhe Junior –
    • for children
    • XPhe Advance / XPhe for2 – for older children, adolescents, adultse
    • Variants with or without additives; tablets, bars, ready-to-consume forms. 
      •  
      (metaX)
  • POA Pharma
    • PKU Easy Microtabs Plus – phenylalanine-free microtablets with vitamins and minerals (Europe). (POA Pharma DE)
  • Cambrooke (Glytactin) – protein substitute products, partly based on glycomacropeptide formulations (available in some European regions). . (Cambrooke DE)

USA – Amino Acid Mixtures

In the United States, similar medical nutrition solutions are available, often from international or U.S.-based medical nutrition manufacturers:

In the United States, similar medical nutrition solutions are available, often from international or U.S.-based medical nutrition manufacturers:

  • Nutricia North America – offers metabolic formulas, including PKU-appropriate products (e.g., specialized amino acid mixtures; Nutricia is also active in North America). (Wikipedia)
  • Lofenalac – phenylalanine-free infant formula powder, traditionally used in the U.S. (especially in pediatric care; often for infants and young children). (Wikipedia)
  • XPhe product lines – marketed in certain U.S. segments, adaptable by age and requirement. (metaX)
  • Product variants from international providers such as Vitaflo and Nutricia are also commonly prescribed in the U.S., sometimes under local labeling or import status. (nestlehealthscience.de)

Tabular Overview by Age Group

Infants (0–12 months)

  • Europe – Known Products
    • PKU start™ – phenylalanine-free infant formula (powder) – Vitaflo (usable from birth). (Vitaflo USA Medical Foodss)
    • Nutricia PKU Anamix Infant – for infants. (Nutricia UK)
    • XPhe Infant Mix LCP (EU/import option). (Nutricia Metabolics)
    • Nutricia Periflex® Early Years – PKU formula for early childhood. (Nutricia Metabolics)
    • PKU explore™ (semi-solid/paste-like dietary form) – Vitaflo (from approx. 6 months). (Nestlé Health Science)
  • USA – Known Products
    • PKU start™ (internationally consistent product line, also available in the USA). (Vitaflo USA Medical Foods)
    • Lofenalac – classic low-phenylalanine infant powder formula (historically used in U.S. practice). (Wikipedia)
    • Nutricia PhenylAde® GMP Mix-In – protein-free mix-in products for supportive nutrition. (Nutricia Metabolics)

Toddlers (1–6 years)

  • Europe – Known Products
    • PKU trio™ and PKU explore™ – Vitaflo (from ~1 year). (Vitaflo USA Medical Foods
    • Nutricia PKU Anamix Junior / Anamix GMPro LQ/Delight variants. (Nutricia Metabolics)
    • PKU GOLIKE family (granules, bars, chewable tablets) – Europe (from ~3 years). (APR.ch)
  • USA – Known Products
    • Nutricia Periflex® Junior Plus (suitable for children and adolescents). (Nutricia Metabolics)
    • Nutricia PhenylAde® Essential Drink Mix – various formulations for children/teenagers. (Nutricia Metabolics
    • Cambrooke Glytactin Series – alternative formulations (imported/prescribed). (Cambrooke DE)

School Age / Adolescents (7–17 years)

  • Europe – Known Products
    • Nutricia PKU Anamix GMPro LQ/Delight, PKU Lophlex LQ/Powder (from age 3 and older). (Nutricia Metabolics)
    • PKU sphere™, PKU express™, etc. – Vitaflo (various formats for children and adolescents). (Nestlé Health Science)
  • USA – Known Products
    • Nutricia PhenylAde® GMP ULTRA, PhenylAde® GMP Drink Mix – PKU formulations for older children, adolescents, and adults. (Nutricia Metabolics)
    • Nutricia PKU Lophlex® LQ/Powder (U.S. Metabolics line). (Nutricia Metabolics)

Adults (18+ years)

  • Europe – Known Products
    • Nutricia PKU GMPro LQ/Delight / Lophlex / Anamix solutions. (Nutricia Metabolics)
    • PKU sphere® / PKU air® (Vitaflo) – suitable for adults. (Nestlé Health Science)
    • PKU Easy Microtabs Plus (Europe, microtablet form) – practical supplement. (POA Pharma DE)
  • USA – Known Products
    • Nutricia PhenylAde® 60 Drink Mix / PhenylAde® MTE Amino Acid Blend / other GMP-based formulations. (Nutricia Metabolics)
    • PKU start™ – not primarily intended, but in some cases used as a base for adults under specialized supervision. (Vitaflo USA Medical Foods)
    • Cambrooke Glytactin / other prescribed protein substitutes. (Cambrooke DE)