Ezetimibe

Ezetimibe inhibits the absorption of cholesterol from the intestine.
It leads to a reduction in LDL cholesterol and an increase in HDL cholesterol.
Statins inhibit the body’s own cholesterol production in the liver.
When this endogenous production is reduced, the body compensates by increasing cholesterol absorption from the intestine.

For this reason, doubling the statin dose does not halve the cholesterol level in the blood but only lowers it by about 6% (the Rule of Six).
Ezetimibe is therefore a useful addition to statin therapy. In cases of statin intolerance, it can also be used as monotherapy.

Ezetimibe is generally well tolerated. Rare side effects include gastrointestinal symptoms, allergic skin reactions, and elevated transaminases.

Dosage of Ezetimibe:
Ezetimibe 10 mg/day