The most common cause of amputations of the lower extremities is diabetes-related. Available health insurance data show that the prevalence of diabetic foot syndrome (DFS) in Germany is between 6.2–10% [1,2]. Consequently, approximately 550,000 to 850,000 people require treatment each year. The major amputation rate per 100,000 people in 2022 for diabetes mellitus was 10.8 [3]. Data from the Diabetes Patient Follow-Up Documentation (DPV) indicate that about one in three to four patients with diabetes will develop DFS during their lifetime [4].
The causes of diabetic foot syndrome include polyneuropathy, micro- and macrovascular diseases, changes in bones and joints, as well as injuries and infections of the feet. In addition to medical and daily foot care, daily self-monitoring of the feet can help detect injuries, skin cracks, and other problems at an early stage and thereby limit the progression of DFS or, if necessary, encourage early consultation at a specialized foot care center.
Self-monitoring of the feet should be part of the daily routine of every patient with diabetes, especially if reduced sensation is already present. In such cases, the feet are considered at-risk or high-risk feet. This leads to preventive measures such as:
In diabetes, the skin is often very dry because:
At higher concentrations, urea has a keratolytic (callus-reducing) effect:
[1] Eckhard M, Lawall H, Lobmann R, Thienel F. Diabetic foot syndrome in times of structural reforms: opportunities and risks. In: German Diabetes Health Report 2024: 103–112.
[2] Jacobs E, Rathmann W. Epidemiology of diabetes. Diabetologie 2017; 12: 437–446.
[3] Robert Koch Institute 2022. Diabetes in Germany.
[4] Bohn B, Grünerbel A, Altmeier M, et al.: Diabetic foot syndrome in patients with diabetes. A multicenter German/Austrian DPV analysis of 33,870 patients. Diabetes Metab Res Rev 2018; 34 (6): e3020.