Treatments for female sexual dysfunction

Treatments for female sexual dysfunction depends on the specific problem (low desire, difficulty with arousal, orgasm problems, pain during sex, or a combination). Most experts use a biopsychosocial approach, addressing medical, hormonal, psychological, and relationship factors together.

Low Sexual Desire (Hypoactive Sexual Desire)

Lifestyle and Medical Optimization

  • Review medications that may reduce libido (e.g., some antidepressants, hormonal contraceptives)
  • Improve sleep, exercise, and stress management
  • Treat underlying conditions such as:
    • Depression
    • Diabetes Mellitus
    • Hypothyroidism

Psychological and Relationship Therapy

  • Sex therapy
  • Cognitive behavioral therapy (CBT)
  • Couples counseling
  • Mindfulness-based interventions

Medications

For selected women with acquired, generalized low sexual desire:

  • Flibanserin
    • Approved in some countries for premenopausal women with hypoactive sexual desire disorder (HSDD)
    • Taken daily
  • Bremelanotide
    • Injectable medication used before anticipated sexual activity
    • Approved in the United States for certain women with HSDD

Testosterone Therapy

  • Sometimes prescribed off-label for postmenopausal women with low desire
  • Usually considered only after careful evaluation
  • Requires monitoring for side effects

Arousal Disorders

Women may have adequate desire but difficulty becoming physically aroused.

Treatment may include:

  • Sex therapy and education
  • Pelvic floor physiotherapy
  • Lubricants and moisturizers
  • Treatment of hormonal deficiencies
  • Addressing medications or medical conditions affecting blood flow or nerve function

Vaginal Dryness and Menopause-Related Symptoms

Common after menopause due to reduced estrogen.

Non-Hormonal Options

  • Vaginal moisturizers
  • Water- or silicone-based lubricants

Hormonal Treatments

  • Local vaginal estrogen preparations
  • Vaginal estrogen creams, tablets, or rings

These can be particularly effective for:

  • Dryness
  • Pain during intercourse
  • Vaginal atrophy

Other Options

  • Ospemifene
  • Prasterone

Pain During Intercourse (Dyspareunia)

Treatment depends on the cause.

Possible approaches include:

  • Treatment of infections
  • Hormonal therapy for vaginal atrophy
  • Pelvic floor physical therapy
  • Pain management strategies
  • Counseling when pain has psychological or relational components

For conditions such as:

  • Vulvodynia
  • Endometriosis

specific medical or surgical treatment may be required.

Orgasm Disorders

Treatment may include:

  • Sexual education and counseling
  • Directed masturbation training
  • Pelvic floor therapy
  • Treatment of contributing medications or medical conditions
  • Sex therapy

No medication is specifically approved solely for female orgasm disorder.

Pelvic Floor Physical Therapy

Often underutilized but very effective for:

  • Pelvic pain
  • Vaginismus
  • Dyspareunia
  • Pelvic floor dysfunction

It may involve:

  • Muscle relaxation techniques
  • Biofeedback
  • Stretching and strengthening exercises

Emerging and Investigational Therapies

Some clinics offer:

  • Platelet-rich plasma (PRP)
  • Energy-based vaginal devices (laser/radiofrequency)
  • Shockwave therapy

However, evidence for these treatments remains limited, and major professional societies generally consider them investigational.

Most Effective Overall Approach

For many women, the best outcomes come from combining:

  1. Identification and treatment of medical causes.
  2. Management of hormonal issues when present.
  3. Pelvic floor therapy if pain or muscle dysfunction exists.
  4. Sex therapy or psychological counseling.
  5. Relationship-focused interventions when relevant.

Unlike male erectile dysfunction, where a single medication such as Sildenafil may often be effective, treatment of female sexual dysfunction is usually more individualized and often combines several approaches.